What is Vogt-Koyanagi-Harada Syndrome (VKH)?
Vogt-Koyanagi-Harada Syndrome is a complex autoimmune condition that affects multiple organs, with notable manifestations in the eyes. Prof. Stanga and his Team at The Retina Clinic London is here to guide you through the intricacies of this syndrome and provide tailored care for your unique needs.
What is Vogt-Koyanagi-Harada Syndrome (VKH)?
Given the complex nature of VKH, there are several clinical features of this condition which are not limited to the eye and include:
- Multisystem Involvement: VKH is characterized by autoimmune reactions affecting not only the eyes but also the skin, auditory system, and central nervous system.
- Bilateral Uveitis: Inflammation often leads to bilateral uveitis, impacting both eyes.
- Fluctuating Symptoms: VKH may present with a range of symptoms, including vision changes, hearing loss, skin pigmentation, and neurological manifestations which can come and go.
In the eyes, VKH specifically manifests with typical formations of fluid pockets underneath the layers of the retina which look as follows: [image]
How is Vogt-Koyanagi-Harada Syndrome diagnosed at The Retina Clinic London?
At The Retina Clinic London, we utilize advanced diagnostic techniques and the latest imaging equipment to accurately identify Vogt-Koyanagi-Harada Syndrome:
Ultrawidefield Multi-Wavelength Fundus Photography:
High-resolution imaging capturing detailed views of up to 80% of the retina and choroid in one image.
Ultra widefield Fundus Fluorescein Angiography and Indocyanine Green Angiography:
This is a specialised imaging technique involving injecting a dye into the vein of your arm and imaging it when it reaches the blood vessels in your eye with a special light wavelength. This information allows your consultant to see the extent of any inflammation, fluid build-up, and lesions in the retina and choroid.
Ultra widefield Optical Coherence Tomography (OCT):
State-of-the-art imaging for cross-sectional views of the retina and choroid, aiding in lesion characterisation.
How is VKH treated and managed at The Retina Clinic London?
Our clinic offers a personalized and multidisciplinary approach to managing VKH. Our ophthalmologists will device a treatment plan that caters to your specific symptoms and reflect your needs. They have on hand the following tools to use in any treatment plan:
Corticosteroids: Targeted administration to reduce inflammation and manage symptoms.
Immunosuppressive Medications: tailored treatments for cases involving recurrent or severe inflammation.
Ongoing Monitoring: regular follow-ups to track progress and adjust treatment plans as needed.
Collaborative Care: coordination with specialists in dermatology, neurology, and audiology for comprehensive management.